Long Covid

[shpalman]

Also be careful not to multiply the most severe symptoms of long covid by the percentage of people who suffered any degree of long-term symptoms post-covid.

[Bird on a Fire]

Yep, I've been f.cking knackered since about March last year, but didn't get covid till I came to England for Christmas.

[Martin_B]

Yep, I've been f.cking knackered since about March last year, ...

I've had that; I think it's called getting old, mate.

[Woodchopper]

Increased risk of diabetes in children after Covid infection: https://www.cdc.gov/mmwr/volumes/71/wr/mm7102e2.htm

Cause unknown.

[raven]

Pancreatic tissue can have ACE-2 receptors, I think, so there's a possible plausible mechanism for damage.

I meant to post this link here: Could microclots help explain the mystery of long Covid?
Seems like a potential explanation for some of the after effects of Covid. Not sure that it'd apply to ME/CFS as they suggest though.

[Woodchopper]

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

https://www.nature.com/articles/s41590-021-01113-x

[FlammableFlower]

Interactions between SARS-CoV-2 N-Protein and α-Synuclein Accelerate Amyloid Formation

Full paper in Chemical Neuroscience here

[Woodchopper]

Cerebrospinal Fluid Offers Clues to Post-COVID ‘Brain Fog’
Over-Stimulated Immune System May Be Impetus to Cognitive Symptoms, UCSF-Led Study Shows

https://www.ucsf.edu/news/2022/01/42215 ... -brain-fog

[Woodchopper]

The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used national healthcare databases from the US Department of Veterans Affairs to build a cohort of 153,760 individuals with COVID-19, as well as two sets of control cohorts with 5,637,647 (contemporary controls) and 5,859,411 (historical controls) individuals, to estimate risks and 1-year burdens of a set of pre-specified incident cardiovascular outcomes. We show that, beyond the first 30 d after infection, individuals with COVID-19 are at increased risk of incident cardiovascular disease spanning several categories, including cerebrovascular disorders, dysrhythmias, ischemic and non-ischemic heart disease, pericarditis, myocarditis, heart failure and thromboembolic disease. These risks and burdens were evident even among individuals who were not hospitalized during the acute phase of the infection and increased in a graded fashion according to the care setting during the acute phase (non-hospitalized, hospitalized and admitted to intensive care). Our results provide evidence that the risk and 1-year burden of cardiovascular disease in survivors of acute COVID-19 are substantial. Care pathways of those surviving the acute episode of COVID-19 should include attention to cardiovascular health and disease.

https://www.nature.com/articles/s41591-022-01689-3

[Herainestold]

Are Putin's actions due to Long Covid?

Although it's not clear if he's had the virus, the Sputnik vaccine is not known to be reliable and after isolating in September after members of his inner circle tested positive he disappeared from view for a long period in October.

The US thinktank The Council For Foreign relations has speculated that, after behaviour and statements that are 'off' and 'not right,' he is suffering brain fog induced by Long Covid.

What's more, the isolation caused by the pandemic itself could have left the 69-year-old even further detached from reality, with one neuropsychologist claiming the 'progressive isolation' could have led to hubris syndrome, which 'diminished his ability to weigh up risk'.

Speaking to FEMAIL, Clinical Director at Medicine Direct. Hussain Abdeh explained how a person's mental state could be uprooted by the virus.

He explained: 'Research early on into the pandemic also found that a small number of people who tested positive for COVID-19 experienced sudden behavioural changes including delirium, confusion, and agitation.'

https://www.dailymail.co.uk/femail/arti ... n-mad.html

[WFJ]

Are Putin's actions due to Long Covid?

Are Putin's actions due to tertiary syphilis?

This question makes just as much sense.

[Herainestold]

Are Putin's actions due to Long Covid?

Are Putin's actions due to tertiary syphilis?

This question makes just as much sense.

It could be both. Long Covid and syphilis.

[bob sterman]

Are Putin's actions due to Long Covid?

Are Putin's actions due to tertiary syphilis?

This question makes just as much sense.

It could be both. Long Covid and syphilis.

I think for Herainestold everything is due to COVID - even COVID is probably due to Long Covid. Brain fog in laboratory workers earlier infected with a version of the coronovirus, led them to get confused and mix up their flask of tea with one containing SARS-CoV-2, when they popped out for lunch at the wet market.

[Woodchopper]

The COVID Heart—One Year After SARS-CoV-2 Infection, Patients Have an Array of Increased Cardiovascular Risks
https://jamanetwork.com/journals/jama/f ... le/2789793

Summary of research posted earlier.

[raven]

That's both concerning and not entirely unexpected for a virus that messes with the cardiovascular system.

I'd like to think vaccines go some way to protect against these longer term problems that are showing up, but I don't know if there's any evidence of that yet.

[Woodchopper]

Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2
https://www.thelancet.com/journals/lanc ... 2/fulltext

tl;dr Omicron has a reduced risk of long covid compared to Delta.

Not surprising as Omicron also has lower risks of hospitalization and death. But still, good to see it in a study.