Has anyone had the vaccine yet?

[Lew Dolby]

I took a book for the wait-time. Buggers insisted I leave before I got to the end of the chapter I was reading !! Wasn't as if they need the seat - was only about half a dozen of us in seating for 3 or 4 dozen.

[Sciolus]

I think some centres have poorer wifi so it takes longer for the microchip to connect and transfer the 5G data.

[veravista]

Mrs V now in bed and decidedly shivery. Looks better than about 30 minutes ago though.

[Fishnut]

Mrs V now in bed and decidedly shivery. Looks better than about 30 minutes ago though.

Oh no, that sounds pretty rough. I hope she feels better soon.


Mum got her vaccine last night. She said it was really well organised. Her only complaint was about finding the entrance to the site which didn't sound particularly well signposted, and differs from the usual entrance route. Apparently she was given the option of waiting inside or in her car for the 15 mins post-jab.

So far she's fine. I think she said her arm was a little sore but nothing worse than a flu vaccination.

[veravista]

She's fine. Got up and had some soup, read for a bit and has gone to bed.

[Lydia Gwilt]

A friend of mine (50 ish marathon runner) said he had a rough couple of days after the second Pfizer dose. Is the response related to how efficient your immune system is?

Possibly, although marathon runners have notoriously poor immune responses.

There's a very long review article here: https://www.frontiersin.org/articles/10 ... 00648/full that argues otherwise.

Their longish summary of the article: Spoiler:

In the first part of this review, we deconstruct the key pillars which lay the foundation to this theory—referred to as the “open window” hypothesis—and highlight that: (i) limited reliable evidence exists to support the claim that vigorous exercise heightens risk of opportunistic infections; (ii) purported changes to mucosal immunity, namely salivary IgA levels, after exercise do not signpost a period of immune suppression; and (iii) the dramatic reductions to lymphocyte numbers and function 1–2 h after exercise reflects a transient and time-dependent redistribution of immune cells to peripheral tissues, resulting in a heightened state of immune surveillance and immune regulation, as opposed to immune suppression. In the second part of this review, we provide evidence that frequent exercise enhances—rather than suppresses—immune competency, and highlight key findings from human vaccination studies which show heightened responses to bacterial and viral antigens following bouts of exercise. Finally, in the third part of this review, we highlight that regular physical activity and frequent exercise might limit or delay aging of the immune system, providing further evidence that exercise is beneficial for immunological health. In summary, the over-arching aim of this review is to rebalance opinion over the perceived relationships between exercise and immune function. We emphasize that it is a misconception to label any form of acute exercise as immunosuppressive, and, instead, exercise most likely improves immune competency across the lifespan.

Marathons and ultramarathons not specifically mentioned in that summary but are discussed in the article. They refer to studies finding that IgA secretion decreased after marathons or 2h rowing sessions - and point out that "contradictory findings are also in abundance but are much less cited in the literature".

THanks for that, I must re-assess my immunology.

[monkey]

Since I had my first jab I have had 2 Covid tests (one since 2nd)*. Both have been negative. I hope this means the vaccine is either working for me, but I suppose if I've not been exposed enough to get The Covids, that just means I'm awesome at masks and distancing. I'm happy either way.

*I now get to scrape my nose every two weeks at work, rather than just being picked at random.

[yoss]

-- I posted the below in the wrong thread, so I've pasted it below, I'll try and delete that other post now! --

Some anecdotal stuff here from South Manchester.

I've just had the first dose, as have two of my close friends. I'm a health 61 year old man. My friends are 51 (male asian athematic), and 41 - heart condition, male. Among our close friendship group of around 10 people aged 40 - 60is only one hasn't yet been offered or had the vaccine. We are fairly unrepresentative, either working in health or social care, having health problems or just being a bit old, but I'm still impressed at the number of us being jabbed.

As to the immunisation centre; it seemed extremely well organised with a steady flow of people being directed through with considerable efficiency.

-- now then; it's back to lurking for me!