Scrutable

Creatine is one supplement that is actually useful (and quite safe) - also in specific situations.

In this new study (which requires further replication/validation) researchers found that adding 5g of creatine supplement to patients with severe depression already on antidepressant medications greatly reduced/improved depression symptoms and quality of life.

Creatine increased energy stores in the brain impacted by depression to improve mental health. It did so by increasing phosphocreatine levels inside the brain and repleting energy stores.

Very cool study. A lot of new direction to use this natural supplement in special population to improve quality of life.

This hypothesis-generating trial suggests that creatine could be a useful and safe supplement to CBT for depression. Longer and larger clinical trials are warranted.