Plus the usual "don't stop taking it" messages, obviously.The FDA has begun testing samples of the diabetes drug metformin for the carcinogen N-Nitrosodimethylamine (NDMA), the agency announced Wednesday. Contamination with this same substance led to recalls of blood pressure and heartburn medications within the last 2 years.
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The FDA's announcement comes on the heels of a recall of three versions of metformin in Singapore and the European Medicines Agency's request that manufacturers test for NDMA, according to Bloomberg News.
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Valisure, an American online pharmacy that tests every batch of drugs it sells before dispensing them, has rejected 60% of its metformin since it started testing for NDMA in March.
This is perhaps a small downside of generic availability, you never quite know where the stuff's coming from, however it's boxed. And whatever protection the EMA can provide probably becomes moot in UKadia soon.
NB: The Singapore authority recalled 3 out of 46 versions of metformin, 2 of them from the same manufacturer. So not a huge problem there, but we really shouldn't be seeing this.
Fun metformin fact, there's so much of this going in and out of people it's detectable in drinking water.