Anything is possible in biology, as the systems are so complex, but it's quite reasonable to assume the same vaccine works best for all groups.Herainestold wrote: ↑Sun Feb 28, 2021 9:07 pmDifferent groups have different susceptibilities and different responses to the virus. Quite large differences in fact.
In treating these different groups you might have to use different strategies and techniques and treatments. So would different vaccines taking into account the differences between groups not make a difference?
It's a bit like dealing with shoplifters. Different shops might be affected in different ways by a thief, but one defence is to distribute a photo of a thief so shopkeepers can recognise them. The same photo works for all shops. Drugs frequently interact with your body to produce an effect, but vaccines are just specimens of something that should be attacked. While one person's immune system may be much better able to attack than another's, that doesn't mean that a different specimen would change that.
However, there are some grounds which might support different vaccines for different people due to the nature of the ones developed for this disease. Vaccines used to be merely weakened or killed versions of the real pathogens, but now we have vaccines which contain only part of the virus (the Oxford one - which is therefore like a photo of the thief's face rather than a full-body shot) and ones which don't contain the virus themselves but cause our bodies to make the relevant part of the virus (Moderna). The latter might well have variable efficacy across different groups, but it's quite reasonable to presume it doesn't until we have evidence that it does.