Massaging data to fit a theory is not the worst research sin
https://www.timeshighereducation.com/op ... search-sin

ISTR Mendel's results from plant breeding were good, good to the point of implausibility.Stupidosaurus wrote: Fri May 01, 2020 9:24 pm Not seeking to agree or justify, but hasn't there been some evidence that some of science's historical leading lights have beautified their data in the past? History written by the victors blah blah. I would dig out an example but I'm lazy and about to watch some sh.tty TV.
https://en.wikipedia.org/wiki/Oil_drop_experimentStupidosaurus wrote: Fri May 01, 2020 9:24 pm Not seeking to agree or justify, but hasn't there been some evidence that some of science's historical leading lights have beautified their data in the past? History written by the victors blah blah. I would dig out an example but I'm lazy and about to watch some sh.tty TV.
Wasn't it that the people counting the results (not Mendel himself) knew the results which Mendel expected, and fudged the results.basementer wrote: Fri May 01, 2020 9:27 pmISTR Mendel's results from plant breeding were good, good to the point of implausibility.Stupidosaurus wrote: Fri May 01, 2020 9:24 pm Not seeking to agree or justify, but hasn't there been some evidence that some of science's historical leading lights have beautified their data in the past? History written by the victors blah blah. I would dig out an example but I'm lazy and about to watch some sh.tty TV.
Yes, apparently his monk underlings are the suspect culprits.Martin_B wrote: Sat May 02, 2020 4:12 amWasn't it that the people counting the results (not Mendel himself) knew the results which Mendel expected, and fudged the results.basementer wrote: Fri May 01, 2020 9:27 pmISTR Mendel's results from plant breeding were good, good to the point of implausibility.Stupidosaurus wrote: Fri May 01, 2020 9:24 pm Not seeking to agree or justify, but hasn't there been some evidence that some of science's historical leading lights have beautified their data in the past? History written by the victors blah blah. I would dig out an example but I'm lazy and about to watch some sh.tty TV.
Warning: I once wrote an article on Cyril Burt.Boustrophedon wrote: Fri May 01, 2020 11:40 pm So if it turns out to be true then it's beautification but if it turns out not to be true it's fraud? How far from the truth was Cyril Burt?
What would be the impact of this shift in paradigm? Obviously in most cases the uterine environment a kid was in was their biological mother's, so what would be changing is the mechanism of heritability. Is the current thinking still that epigenetic mechanisms often reflect not just the mother's inherent state but also environmental factors, stress etc. - in which case we'd be looking at a mixture of biological and social effects masquerading as purely biological? Or am I way off (neither developmental biology nor humans are my areaAllo V Psycho wrote: Thu May 14, 2020 5:05 pm What if correlations between twins and children and parents are due, not to the genetics of inheritance, but to the influence of the uterine environment? In other words, epigenetic, rather than genetic? That would be useful to know.
Yes, that about it. Wikipedia on the Barker hypothesis isn't bad (and I once was a developmental biologist, so that's where I got into it). I'll copy a bit from the Wiki, because it might possibly have some current relevance...Bird on a Fire wrote: Thu May 14, 2020 5:31 pm Very interesting post, thanks AvP.
I'd like to ask about this bit:
What would be the impact of this shift in paradigm? Obviously in most cases the uterine environment a kid was in was their biological mother's, so what would be changing is the mechanism of heritability. Is the current thinking still that epigenetic mechanisms often reflect not just the mother's inherent state but also environmental factors, stress etc. - in which case we'd be looking at a mixture of biological and social effects masquerading as purely biological? Or am I way off (neither developmental biology nor humans are my areaAllo V Psycho wrote: Thu May 14, 2020 5:05 pm What if correlations between twins and children and parents are due, not to the genetics of inheritance, but to the influence of the uterine environment? In other words, epigenetic, rather than genetic? That would be useful to know.).
DNA dominance is the current paradigm (along with the political paradigm of 'The poor deserve it"). When I was at Primary School, they made us sing:Pregnancy outcomes can impact the wellbeing of a society. Comparisons between the children who were in gestation during the 1918 flu pandemic and those in gestation immediately before or after the health crisis show marked differences between the two groups on census data. Across all socioeconomic measures, those who were fetuses during the crisis attained lower educational achievement, income, and socioeconomic status. Specifically, individuals affected were 15% less likely to graduate high school, 15% more likely to be poor, and 20% more likely to be disabled as adults. Even federal welfare payments were higher for the gestational cohort than those born before or after the flu hit.[2] The same economic researcher, Douglas Almond, has investigated other historical situations affecting particular cohorts of fetuses: children born during or immediately following the Chernobyl nuclear disaster explosion, and China's Great Leap Forward (which resulted in a deadly famine). Both prenatally exposed groups suffered lower cognitive abilities and reduced employment levels.[2] Such outcomes can have lasting impacts on the productivity and economic security of a society for an entire generation of individuals, and perhaps even continue to affect future descendants through changes in gene expression.